Journal: Cells

Article Title: Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

doi: 10.3390/cells9040931

Figure Lengend Snippet: Characterization of mouse models from the Translational Vision Research Models (TVRM) program at JAX. A fundus image (circular panels) and corresponding OCT B-scan are shown for homozygous ( a ) Rpgrip1 nmf247 , at one month of age; ( b ) Nmnat1 tvrm113 , at two months; ( c ) Alms1 Gt(XH152)Byg , at one year; and ( d ) Ctnna1 Tvrm5 , at two years. Age-matched OCT and fundus images for C57BL6/J control mice are shown to the right of the mutant images. PR cell loss is indicated by a decreased ONL thickness. Fundus images were acquired using a Micron III or IV retinal camera. The vertical dimension of OCT images was doubled to emphasize changes in retinal layer thicknesses.

Article Snippet: Fundus photographs of EMR mutants were taken in unanesthetized mice treated with 1% cyclopentolate to dilate or enlarge the pupil with an in vivo bright field retinal imaging microscope equipped with image-guided OCT capabilities (Micron III; Phoenix Laboratories, Inc., Pleasanton, CA, USA) as previously described [ ].

Techniques: Mutagenesis

Journal: Frontiers in Bioengineering and Biotechnology

Article Title: Clinical Data for Parametrization of In Silico Bone Models Incorporating Cell-Cytokine Dynamics: A Systematic Review of Literature

doi: 10.3389/fbioe.2022.901720

Figure Lengend Snippet: Osteocyte number measurements in postmenopausal women, in ascending order.

Article Snippet: mullender 2005 ( ) , 271.3/mm 2 ≈ 33,913/mm 3 222.6/mm 2 ≈ 27,825/mm 3 , non-OPE OP , 64.4 69.6 , 53 , Transiliac bone biopsy , bright-field light microscope with TAS + image analyzer TAS + by Leitz, Wetzlar, Germany ×25 magnification , 7 μm , 4.

Techniques: Light Microscopy, Staining, Microscopy